Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol

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Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol.

BACKGROUND The cholecalciferol inputs required to achieve or maintain any given serum 25-hydroxycholecalciferol concentration are not known, particularly within ranges comparable to the probable physiologic supply of the vitamin. OBJECTIVES The objectives were to establish the quantitative relation between steady state cholecalciferol input and the resulting serum 25-hydroxycholecalciferol co...

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Evaluation of Relative Bioavailability of 25-Hydroxycholecalciferol to Cholecalciferol for Broiler Chickens

This study was conducted to evaluate the relative bioavailability (RBV) of 25-hydroxycholecalciferol (25-OH-D3) to cholecalciferol (vitamin D3) in 1- to 21-d-old broiler chickens fed with calcium (Ca)- and phosphorus (P)-deficient diets. On the day of hatch, 450 female Ross 308 broiler chickens were assigned to nine treatments, with five replicates of ten birds each. The basal diet contained 0....

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Kinetics of serum 25-hydroxyvitamin D in haemodialysis patients treated with monthly oral cholecalciferol

BACKGROUND We previously reported that oral cholecalciferol (CCF) (100 000 IU) taken monthly by haemodialysis patients is effective in accomplishing serum 25-hydroxyvitamin D (25-D) levels >75 nmol/L in >80% of cases. We aimed to study the weekly kinetecs of serum 25-D in HD patients receiving oral CCF during the first 6 months of HD. METHODS All new HD patients at our dialysis centre during ...

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Comparison of the Micellar Incorporation and the Intestinal Cell Uptake of Cholecalciferol, 25-Hydroxycholecalciferol and 1-α-Hydroxycholecalciferol

In the context of the global prevalence of vitamin D insufficiency, we compared two key determinants of the bioavailability of 3 vitamin D forms with significant biopotencies: cholecalciferol, 25-hydroxycholecalciferol and 1-α-hydroxycholecalciferol. To this aim, we studied their incorporation into synthetic mixed micelles and their uptake by intestinal cells in culture. Our results show that 1...

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The Response to 25-hydroxycholecalciferol and Dichloromethylene Diphosphate Therapy

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2003

ISSN: 0002-9165,1938-3207

DOI: 10.1093/ajcn/77.1.204