Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1
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چکیده
منابع مشابه
Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1
Some Staphylococcus aureus isolates produced toxic shock syndrome toxin-1 (TSST-1) which is a pyrogenic toxin superantigen (PTSAg). The toxin activates a large fraction of peripheral blood T lymphocytes causing the cells to proliferate and release massive amounts of pro-inflammatory cytokines leading to a life-threatening multisystem disorder: toxic shock syndrome (TSS). PTSAg-mediated-T cell s...
متن کاملIdentification of Toxic Shock Syndrome Toxin-1 (TSST-1) gene in Staphylococcus aureus isolated from bovine mastitis milk
Staphylococcus aureus is a major causative pathogen of clinical and subclinical mastitis of dairy domestic ruminants. This agent produces a variety of extracellular toxins and virulence factors including Toxic Shock Syndrome Toxin-1 (TSST-1) which is the major cause of Toxic Shock Syndrome (TSS). In this study 58 S. aureus isolates obtained from 9 dairy herds in East and West Azerbaijan provinc...
متن کاملDistribution of tsst-1 and mecA Genes in Staphylococcus aureus Isolated From Clinical Specimens.
BACKGROUND Staphylococcus aureus is a harmful pathogen known to express numerous virulence factors and cause severe infections. High levels of methicillin-resistant Staphylococcus aureus (MRSA) strains are one of the important healthcare problems because of the inefficient treatment of these infections. OBJECTIVES The purpose of the current study is to evaluate the incidence of the toxic shoc...
متن کاملPrevalence of toxic shock syndrome toxin 1 (TSST-1)-producing strains of Staphylococcus aureus and antibody to TSST-1 among healthy Japanese women.
Many cases of neonatal toxic shock syndrome (TSS)-like exanthematous disease but few cases of menstrual TSS (mTSS) have been reported in Japan. We determined the prevalence of mucosal colonization with Staphylococcus aureus and of positive antibodies to TSS toxin 1 (TSST-1) among 209 healthy Japanese women in Tokyo. S. aureus isolates from mucosal sites were characterized with respect to TSST-1...
متن کاملdistribution of tsst-1 and meca genes in staphylococcus aureus isolated from clinical specimens
conclusions our outcomes showed elevated incidences of tsst-1 positive and mrsa strains with higher rates of antibiotic resistance. the conflict between our findings and other records may be due to differences in geographic regions. materials and methods the presence of the tsst-1 and meca genes was investigated by polymerase chain reaction (pcr) among s. aureus isolated from 197 clinical sampl...
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ژورنال
عنوان ژورنال: Toxins
سال: 2017
ISSN: 2072-6651
DOI: 10.3390/toxins9020050