Human Picobirnaviruses Identified by Molecular Screening of Diarrhea Samples
نویسندگان
چکیده
منابع مشابه
Divergent Picobirnaviruses in Human Feces
The near-complete genomes of two picobirnaviruses (PBVs) in diarrheal stool samples, human picobirnaviruses D and E (HuPBV-D and -E), were genetically characterized. Their RNA-dependent RNA polymerase (RdRp) protein sequences had <66% identities to known PBVs. Due to a single nucleotide insertion, the open reading frame 2 (ORF2) in segment 1 of HuPBV-D was interrupted by a stop codon. A small s...
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The identification of new virus species is a key issue for the study of infectious disease but is technically very difficult. We developed a system for large-scale molecular virus screening of clinical samples based on host DNA depletion, random PCR amplification, large-scale sequencing, and bioinformatics. The technology was applied to pooled human respiratory tract samples. The first experime...
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1. Mankertz A, Mihneva Z, Gold H, Baumgarte S, Baillot A, Helble R, et al. Spread of measles virus D4-Hamburg, Europe, 2008–2011. Emerg Infect Dis. 2011;17:1396–401. 2. Muscat M. Who gets measles in Europe? J Infect Dis. 2011;204(Suppl 1):S353–65. http://dx.doi.org/10.1093/infdis/jir067 3. Centers for Disease Control and Prevention. Increased transmission and outbreaks of measles—European Regio...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2010
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.02452-09