Human pharmacology of narcotic antagonists.

Clinical pharmacology of calcium antagonists. Satellite symposium on calcium antagonists.

A new class of agents has been made available for the treatment of hypertension. These calcium antagonists have rapid bioavailability and dramatic antihypertensive effects through reduction of total peripheral resistance and the vascular resistance of the major target organs of the body. These changes are usually associated with unchanged cardiac output, preserved organ blood flows, maintained ...

Narcotic Antagonists: The Search for Long-Acting Preparations, 4

S 7 DEVELOPMENT OF POLYLACTIC/GLYCOLIC ACID DELIVERY SYSTEMS FOR USE IN TREATMENT OF NARCOTIC ADDICTION A.D. Schwope, D.L. Wise, J.F. Howes 13 DEVELOPMENT OF INJECTABLE MICROCAPSULES FOR USE IN THE TREATMENT OF NARCOTIC ADDICTION C. Thies 19 LONG-ACTING NARCOTIC ANTAGONIST COMPLEXES A.P. Gray, W.J. Guardina 21 SUSTAINED RELEASE OF NALTREXONE FROM GLYCERIDE IMPLANTS M.F. Sullivan, D.R. Kalkwarf ...

Narcotic antagonists: naltrexone pharmacochemistry and sustained-release preparations.

– Pharmacology of Muscle Relaxants and Their Antagonists

In 1942 Griffith and Johnson suggested that d-tubocurarine (dTc) is a safe drug to use during surgery to provide skeletal muscle relaxation. One year later, Cullen described its use in 131 patients who had received general anesthesia for their surgery. In 1954, Beecher and Todd reported a sixfold increase in mortality in patients receiving dTc versus those who had not received a relaxant. The i...

Calcium antagonists. Pharmacology and clinical research.

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