Human Parainfluenza Type 4 Infections, Canada

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Human Parainfluenza Type 4 Infections, Canada

H parainfluenza viruses (HPIVs) have been recognized as a cause of respiratory tract infections for many decades. They belong to the Paramyxoviridae family, subfamily Paramyxovirinae, and are classified into 4 serotypes. Serotype 4 can be further subdivided into 2 antigenic subtypes, HPIV-4A and HPIV-4B (1). Although the epidemiology and clinical manifestations of serotypes HPIV-1 to HPIV-3 are...

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Human parainfluenza virus surveillance in pediatric patients with lower respiratory tract infections: a special view of parainfluenza type 4.

OBJECTIVE Characterize the role of human parainfluenza virus and its clinical features in Brazilian children under 2 years of age presenting with acute lower respiratory tract infections. METHODS Real-time assays were used to identify strains of human parainfluenza virus and other common respiratory viruses in nasopharyngeal aspirates. One thousand and two children presenting with acute lower...

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Human Parechovirus Infections in Canada

A new reverse transcription-polymerase chain reaction assay was developed for identification of 28 Canadian human parechovirus (HPeV) isolates, including 20 HPeV-1, 3 HPeV-2, and 5 HPeV-3, recovered from 1985 to 2004. All HPeV-1 isolates but 1 were genetically distinct from the Harris reference strain. One HPeV-2 isolate was related to the Williamson strain; the other 2 were related to the Conn...

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Filamentous particle formation by human parainfluenza virus type 2.

Some paramyxoviruses form long filamentous virus particles: however, the determinants of filament formation and the role of such particles in virus transmission and pathogenicity are not clearly defined. By using conventional immunofluorescence microscopy, we found that human parainfluenza virus type 2 (HPIV2) forms filamentous particles ranging from 5 to 15 microm in length in virus-infected, ...

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Influenza and parainfluenza viral infections in children.

• On the basis of strong epidemiologic evidence, influenza and parainfluenza viruses are responsible for significant morbidity and mortality in young infants and children and in persons with chronic medical conditions. (1)(4)(26)(27)(35). • On the basis of research evidence, influenza vaccines are effective in preventing disease in high-risk individuals. (8)(17)(18). • On the basis of strong re...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2006

ISSN: 1080-6040

DOI: 10.3201/eid1211.060196