Human osteoblast damage after antiseptic treatment

Antiseptic Treatment of Necrosis

A lad about fourteen years of age, was admitted into the dispensary 9th November, 18(38, suffering from necrosis of the right tibia: numerous sinuses led down to the bone, and the limb presented a most unnatural appearance from the combined presence in it of portions of nearly two shafts of tibiae, the newly formed bone, and part of the dead one in course of absorption. The lad's general health...

Suprathel-antiseptic matrix: in vitro model for local antiseptic treatment?

Acetic acid is a traditional antiseptic agent that has been used for more than 6000 years. The main goal of this study was to demonstrate the suitability of Suprathel (PolyMedics Innovations GmbH, Denkendorf, Germany) in combination with various antiseptic agents to create an "antiseptic-matrix" especially designed for problematic microorganisms such as Proteus vulgaris, Acinetobacter baumannii...

Antiseptic Treatment of Mammary Abscess

Bone Marrow Osteoblast Damage by Chemotherapeutic Agents

Hematopoietic reconstitution, following bone marrow or stem cell transplantation, requires a microenvironment niche capable of supporting both immature progenitors and stem cells with the capacity to differentiate and expand. Osteoblasts comprise one important component of this niche. We determined that treatment of human primary osteoblasts (HOB) with melphalan or VP-16 resulted in increased p...

The Antiseptic Method of Treatment in Surgery

directed towards the prevention of the evil effects that the germinal matter floating in the air is supposed to be capable of producing. But, whether we admit their hypotheses or not, I cannot but think that some of us have been unjust in so long refusing to test by actual experiment the validity of the precepts of so profound a pathologist, and so experienced a surgeon, as Professor Lister. No...