Human meiosis VIII. Chromosome pairing and formation of the synaptonemal complex in oocytes
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چکیده
منابع مشابه
Hormad1 Mutation Disrupts Synaptonemal Complex Formation, Recombination, and Chromosome Segregation in Mammalian Meiosis
Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata. The homologues connect via axial elements and numerous transverse filaments to form the synaptonemal complex. The synaptonemal complex is a critical component for chromosome pairing, segregation, and recombination. We previously identifie...
متن کاملIn vivo analysis of synaptonemal complex formation during yeast meiosis.
During meiotic prophase a synaptonemal complex (SC) forms between each pair of homologous chromosomes and is believed to be involved in regulating recombination. Studies on SCs usually destroy nuclear architecture, making it impossible to examine the relationship of these structures to the rest of the nucleus. In Saccharomyces cerevisiae the meiosis-specific Zip1 protein is found throughout the...
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References http://genesdev.cshlp.org/cgi/content/full/20/15/1986#References This article cites 56 articles, 22 of which can be accessed free at: service Email alerting click here top right corner of the article or Receive free email alerts when new articles cite this article sign up in the box at the Topic collections (25 articles) Chromosome Dynamics and Nuclear Architecture (42 articles) D...
متن کاملMeiosis in Mice without a Synaptonemal Complex
The synaptonemal complex (SC) promotes fusion of the homologous chromosomes (synapsis) and crossover recombination events during meiosis. The SC displays an extensive structural conservation between species; however, a few organisms lack SC and execute meiotic process in a SC-independent manner. To clarify the SC function in mammals, we have generated a mutant mouse strain (Sycp1(-/-)Sycp3(-/-)...
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ژورنال
عنوان ژورنال: Carlsberg Research Communications
سال: 1983
ISSN: 0105-1938
DOI: 10.1007/bf02911920