Human Herpesvirus-8 Positive Multicentric Castleman’s Disease with Complete Response after Rituximab Monotherapy: A Case Report

Castleman’s disease is a rare non-neoplastic lymphoproliferative disorder of unknown origin. It classified into unicentric or multicentric based on its anatomical distribution. Multicentric can be subdivided according to the presence human herpesvirus-8 (HHV-8) infection. has incidence, and HHV-8-positive even rarer. There are several types natural course for this disease, rapidly progressing type lead death within few weeks, emphasizing need prompt diagnosis treatment. We report recent case from Korea, presenting with multiple lymphadenopathies, confirmed as through biopsy, achieving complete response rituximab monotherapy.