Human estrogen sulfotransferase (SULT1E1) pharmacogenomics: gene resequencing and functional genomics
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چکیده
منابع مشابه
Human estrogen sulfotransferase (SULT1E1) pharmacogenomics: gene resequencing and functional genomics.
1. Estrogens are used as drugs and estrogen exposure is a risk factor for hormone-dependent diseases such as breast cancer. Sulfate conjugation is an important pathway for estrogen metabolism. The sulfotransferase (SULT) enzyme SULT1E1 has the lowest K(m) values for estrogens and catecholestrogens of the 10 known human SULT isoforms. 2. We previously cloned and characterized the human SULT1E1 c...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2003
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0705369