Human eosinophils synthesize and secrete interleukin-6, in vitro

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Human eosinophils synthesize and secrete interleukin-6, in vitro.

Using the technique of in situ hybridization, we have shown that resting, unstimulated, human peripheral blood eosinophils, obtained from subjects with greater than 8% eosinophilia, transcribe and translate messenger RNA (mRNA) for interleukin-6 (IL-6). After incubation for 24 hours in culture medium alone, approximately 19% of eosinophils were positive for IL-6 mRNA. This may be a reflection o...

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Human platelets secrete chemotactic activity for eosinophils.

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ژورنال

عنوان ژورنال: Blood

سال: 1992

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v80.6.1496.1496