Human Antigen-Specific Regulatory T Cells Generated by T Cell Receptor Gene Transfer
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چکیده
منابع مشابه
Human Antigen-Specific Regulatory T Cells Generated by T Cell Receptor Gene Transfer
BACKGROUND Therapies directed at augmenting regulatory T cell (Treg) activities in vivo as a systemic treatment for autoimmune disorders and transplantation may be associated with significant off-target effects, including a generalized immunosuppression that may compromise beneficial immune responses to infections and cancer cells. Adoptive cellular therapies using purified expanded Tregs repre...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0011726