Human and rodent humoral immune responses to Andes virus structural proteins

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Human and rodent humoral immune responses to Andes virus structural proteins.

In the present work we identified B-cell epitopes recognized by sera of humans and rodents naturally infected with Andes virus, a hantavirus present in Chile and Argentina. Analysis of patient and rodent sera with overlapping peptides revealed 21 human and rodent epitopes on the three structural proteins. Whereas in the nucleoprotein the region comprising aa 248-260 was shown to be the key dete...

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ژورنال

عنوان ژورنال: Virology

سال: 2005

ISSN: 0042-6822

DOI: 10.1016/j.virol.2005.01.031