Human and Microbial Proteins From Corpora Amylacea of Alzheimer’s Disease
نویسندگان
چکیده
منابع مشابه
Spinal corpora amylacea and motor neuron disease: a quantitative study.
OBJECTIVE To test the hypothesis that as there is growing evidence that corpora amylacea, or amyloid bodies, in the CNS are derived primarily from neurons, it might be expected that their numbers in the spinal cord would decline with loss of neurons in motor neuron degeneration as they do in the retina on destruction of ganglion cells by glaucoma. METHODS The numbers of corpora amylacea were ...
متن کاملAmyloid in prostatic corpora amylacea.
AIM To determine the presence and nature of amyloid in prostatic corpora amylacea using immunohistological studies. METHODS Prostatic tissue from 18 transurethral and two open resection specimens was studied. Paraffin wax embedded tissue sections were stained with haematoxylin and eosin and the alkaline Congo red method with and without previous treatment with potassium permanganate. Sections...
متن کاملCorpora Amylacea in Human Cadaveric Brain Age Related Differences
The present study was designed to investigate the age related deposits of corpora amylacea (CA) in the human cadaveric brain. It is an observational study which was conducted in the Department of Anatomy, University of Health Sciences, Lahore. The duration of the study was two years. Sixty brain specimens (age 19-72 years) from cadavers were collected from the mortuary of the King Edward Medica...
متن کاملNew perspectives on corpora amylacea in the human brain
Corpora amylacea are structures of unknown origin and function that appear with age in human brains and are profuse in selected brain areas in several neurodegenerative conditions. They are constituted of glucose polymers and may contain waste elements derived from different cell types. As we previously found on particular polyglucosan bodies in mouse brain, we report here that corpora amylacea...
متن کاملLocalization of blood proteins thrombospondin1 and ADAMTS13 to cerebral corpora amylacea.
Corpora amylacea (CA) have long been described in aging brains and in patients with neurodegenerative conditions, but their origins have been debated. It has been proposed that CA represent collections of nervous system breakdown products that accumulate within astrocytic cytoplasm. In support of this, studies have shown that CA include glycosylated material, ubiquitin, and an assortment of pro...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-28231-1