Human ACE gene polymorphism and distilled water induced cough
نویسندگان
چکیده
منابع مشابه
Human ACE gene polymorphism and distilled water induced cough.
BACKGROUND Inhibitors of angiotensin converting enzyme (ACE) cause a non-productive cough. The insertion/deletion polymorphism of ACE was used as a genetic marker to investigate the relationship between ACE genotype and cough sensitivity. METHODS A double blind cough challenge was performed in 66 normotensive subjects (34 men) of mean age 34.8 years (range 18-80) using aerosols of distilled w...
متن کاملRapid communication Human ACE gene polymorphism and distilled water induced cough
to an Alu repetitive sequence 287 base pairs (bp) long has been described. The ACE inBackground – Inhibitors of angiotensin converting enzyme (ACE) cause a nonsertion/deletion polymorphism was found to be associated with serum levels of ACE and, in productive cough. The insertion/deletion polymorphism of ACE was used as a gensubjects who are homozygous for the D allele, the mean serum level of ...
متن کاملAngiotensin-Converting Enzyme (ACE) Gene Insertion/Deletion Polymorphism and ACE Inhibitor-Related Cough: A Meta-Analysis
OBJECTIVE An insertion/deletion (I/D) variant in the angiotensin-converting enzyme (ACE) gene was associated with ACE inhibitor (ACEI)-related cough in previous studies. However, the results were inconsistent. Our objective was to assess the relationship between the ACE I/D polymorphism and ACEI-related cough by meta-analysis and to summarize all studies that are related to ACE I/D polymorphism...
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Discrepancies in angiotensin-1 converting enzyme (ACE) allele genetic susceptibility with disease etiology have been attributed to ethnic differences. We investigated ACE gene polymorphism of the multiethnic Malaysian population by utilizing nested polymerase chain reaction. Allelic frequency of 0.65 and 0.35 for I and D allele, respectively in the pooled population was comparable with other As...
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Great personal enthusiasm, temptation, technical efforts, and complex mathematical equations characterize the developing research field of newly identified gene polymorphisms and their impact on a variety of cardiovascular diseases. After the first publication of Cambien and coworkers1 in Nature in 1992, who reported that the D/D angiotensinconverting enzyme (ACE) polymorphism is a potent risk ...
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ژورنال
عنوان ژورنال: Thorax
سال: 1997
ISSN: 0040-6376
DOI: 10.1136/thx.52.2.111