HPLC method validation for quantification of tetrahydrocurcumin in bulk drug and formulation
نویسندگان
چکیده
منابع مشابه
RP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms
A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...
متن کاملRP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms
A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...
متن کاملDevelopment and validation of UV and RP-HPLC method for estimation of Nepafenac in bulk drug and opthalmic formulation
Introduction Nepafenac (NEPA), [2-(2-amino 3-benzoyl phenyl) acetamide] (Figure 1) is Antiinflammatory (NSAID’s) which is indicated for the treatment of pain and inflammation associated with cataract surgery. NEPA is a prodrug. After penetrating the cornea, NEPA undergoes rapid bioactivation to amfenac, which is a potent NSAID that uniformly inhibits the COX1 and COX2 activity. [1] Amfenac is t...
متن کاملValidated HPLC Method for Simultaneous Quantitation of Diclofenac Sodium and Misoprostol in Bulk Drug and Formulation
HPLC method has been described for simultaneous determination of Diclofenac Sodium and Misoprostol in formulation. This method is based on HPLC separation of the two drugs on the Thermo Hypersil BDS–C18 (250 mm × 4.6 mm, 5.0 μ) from Germany with isocratic conditions and simple mobile phase containing acetonitrile: water (85: 15) at flow rate of 1 mL/min using UV detection at 220 nm. This method...
متن کاملRapid RP-HPLC method for the quantification of glabridin in crude drug and in polyherbal formulation.
A simple, economic, selective, precise and robust method has been developed and validated for the analysis of glabridin in crude drugs and polyherbal formulations. Reversed-phase chromatography is performed on a C18 column with water and acetonitrile as mobile phase in gradient elution method at a flow rate of 1 mL/min. Detection is performed at 230 nm and a sharp peak is obtained for glabridin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Future Journal of Pharmaceutical Sciences
سال: 2021
ISSN: 2314-7253
DOI: 10.1186/s43094-021-00194-7