HOXB4 homeodomain protein is expressed in developing epidermis and skin disorders and modulates keratinocyte proliferation
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چکیده
منابع مشابه
The MAGUK-family protein CASK is targeted to nuclei of the basal epidermis and controls keratinocyte proliferation.
The Ca2+/calmodulin-associated Ser/Thr kinase (CASK) binds syndecans and other cell-surface proteins through its PDZ domain and has been implicated in synaptic assembly, epithelial polarity and neuronal gene transcription. We show here that CASK regulates proliferation and adhesion of epidermal keratinocytes. CASK is localised in nuclei of basal keratinocytes in newborn rodent skin and developi...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2002
ISSN: 1058-8388
DOI: 10.1002/dvdy.10085