Hox gene variation and evolution
نویسندگان
چکیده
منابع مشابه
Hox gene variation and evolution.
8 annually degasses about 1 gigatonne (10 tonnes) of CO2 (ref. 3), equivalent to 20 per cent of current anthropogenic output. The regression lines and intercepts of dissolved inorganic carbon, silicate and nitrate concentrations, measured in the upper 200 m of the EUZ, indicate that silicate availability regulates both carbon and nitrate uptake and fate. The slope of the highly significant regr...
متن کاملVariation and constraint in Hox gene evolution.
Despite enormous body plan variation, genes regulating embryonic development are highly conserved. Here, we probe the mechanisms that predispose ancient regulatory genes to reutilization and diversification rather than evolutionary loss. The Hox gene fushi tarazu (ftz) arose as a homeotic gene but functions as a pair-rule segmentation gene in Drosophila. ftz shows extensive variation in express...
متن کاملGenomic evolution of Hox gene clusters.
The family of Hox genes, which number 4 to 48 per genome depending on the animal, control morphologies on the main body axis of nearly all metazoans. The conventional wisdom is that Hox genes are arranged in chromosomal clusters in colinear order with their expression patterns on the body axis. However, recent evidence has shown that Hox gene clusters are fragmented, reduced, or expanded in man...
متن کاملHox Gene Loss during Dynamic Evolution of the Nematode Cluster
HOX GENES ARE IMPORTANT: their central role in anterior-posterior patterning provides a framework for molecular comparison of animal body plan evolution. The nematode Caenorhabditis elegans stands out as having a greatly reduced Hox gene complement. To address this, orthologs of C. elegans Hox genes were identified in six species from across the Nematoda, and they show that rapid homeodomain se...
متن کاملEvolution of microRNAs located within Hox gene clusters.
MicroRNAs (miRNAs) form an abundant class of non-coding RNA genes that have an important function in post-transcriptional gene regulation and in particular modulate the expression of developmentally important transcription factors including Hox genes. Two families of microRNAs are genomically located in intergenic regions in the Hox clusters of vertebrates. Here we describe their evolution in d...
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ژورنال
عنوان ژورنال: Nature
سال: 1998
ISSN: 0028-0836,1476-4687
DOI: 10.1038/34530