How to treat recurrences after Avastin treatment for neovascular AMD: stick to Avastin or switch to Lucentis?

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How to treat recurrences after Avastin treatment for neovascular AMD: stick to Avastin or switch to Lucentis?

Before the recent approvement of ranibizumab (Lucentis) for the treatment of neovascular age-related macular degeneration (AMD), bevazicumab (Avastin) had been successfully used as an off-label treatment for this condition. As a consequence, in daily practice we are confronted with a large number of patients having received Avastin injections in the past, now facing a recurrence of the disease ...

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Switch to aflibercept or ranibizumab after initial treatment with bevacizumab in eyes with neovascular AMD

BACKGROUND To evaluate changes in central macular thickness (CMT) and visual outcome in patients with neovascular age-related macular degeneration (AMD) treated initially with bevacizumab and subsequently switched to either aflibercept or ranibizumab. METHODS Observational clinical study was performed. We measured the structural outcome (CMT on SD-OCT; μm) and the visual outcome (best correct...

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Feasibility and efficacy of a mass switch from ranibizumab (Lucentis) to bevacizumab (Avastin) for treatment of neovascular age-related macular degeneration.

PURPOSE To assess the feasibility and potential obstacles of a departmental switch from ranibizumab (Lucentis, Genentech, South San Francisco, CA) to bevacizumab (Avastin, Genentech) for the treatment of neovascular age-related macular degeneration (AMD). METHODS A total of 154 eyes treated for wet AMD with ranibizumab or bevacizumab were examined over a 10-month period. The treatment protoco...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2008

ISSN: 0007-1161

DOI: 10.1136/bjo.2008.138396