How to prevent steroid induced osteoporosis
نویسندگان
چکیده
منابع مشابه
How to prevent steroid induced osteoporosis.
The first choice for prevention of corticosteroid osteoporosis is a potent oral bisphosphonate-for example, alendronate or risedronate. Intravenous bisphosphonates should be considered for patients intolerant of the oral route. For patients receiving chronic low dose corticosteroids treatment with calcium and vitamin D may prevent further bone loss. Use of parathyroid hormone is promising.
متن کاملSteroid-induced osteoporosis.
INTRODUCTION Corticosteroids have major effects on calcium metabolism, leading to accelerated osteoporosis and fracture. METHODS This review will attempt to summarise current knowledge about their effects in light of new information and important remaining questions, especially with respect to management of this common condition. RESULTS Corticosteroids affect bone through multiple pathways...
متن کاملSteroid-induced osteoporosis: how can it be avoided?
In 1932, Harvey Cushing wrote: ‘The greatly compressed bodies of the vertebrae ... were so soft they could easily be cut with a knife’. Today, steroid-induced osteoporosis is still of major clinical relevance. Glucocorticosteroids induce a biphasic bone loss with a rapid initial phase of ;10–15% during the first few months and a slower phase of ;2–5% annually. As shown in Figure 1, steroids do ...
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Chronic use of corticosteroid is the most common secondary cause of osteoporosis. Contrary to previous belief apart from the primary or the idiopathic type, it occurs in all racial groups, both genders, and at any age. In a large cross sectional study in which 229 corticosteroid users (mean age 61 years, ≥6 months of prednisone, ≥5 mg/day) were compared with 286 controls not taking corticostero...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2005
ISSN: 0003-4967
DOI: 10.1136/ard.2003.018556