How Proteins Adapt: Lessons from Directed Evolution
نویسندگان
چکیده
منابع مشابه
How proteins adapt: lessons from directed evolution.
Applying artificial selection to create new proteins has allowed us to explore fundamental processes of molecular evolution. These "directed evolution" experiments have shown that proteins can readily adapt to new functions or environments via simple adaptive walks involving small numbers of mutations. With the entire "fossil record" available for detailed study, these experiments have provided...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Symposia on Quantitative Biology
سال: 2009
ISSN: 0091-7451,1943-4456
DOI: 10.1101/sqb.2009.74.046