How did cyclophosphamide become the drug of choice for lupus nephritis?
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منابع مشابه
How did cyclophosphamide become the drug of choice for lupus nephritis?
Thirty years ago, Donadio and colleagues published the results of a randomized study in 50 patients with diffuse proliferative lupus nephritis and reduced creatinine clearance [1]. The patients were randomly assigned to either prednisone alone or prednisone in combination with oral cyclophosphamide (CTX). The corticosteroid-only group received 60 mg daily for 1 to 3 months, and then tapered to ...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2008
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfn640