How Amylases Achieve Their Perfect Stereoselectivity.

How people achieve their amazing temporal precision in interception.

People can hit rapidly moving balls with amazing precision. To determine how they manage to do so, we explored how various factors that we could manipulate influenced people's precision when intercepting virtual targets. We found that temporal precision was highest for fast targets that subjects were free to intercept wherever they wished. Temporal precision was much poorer when the point of in...

Pitch perfect: how fruit flies control their body pitch angle.

Flapping insect flight is a complex and beautiful phenomenon that relies on fast, active control mechanisms to counter aerodynamic instability. To directly investigate how freely flying Drosophila melanogaster control their body pitch angle against such instability, we perturbed them using impulsive mechanical torques and filmed their corrective maneuvers with high-speed video. Combining experi...

How to achieve composability?

In systemsand software architecting, architecture can be viewed as a highlevel design that supports the construction of ICT-systems. Starting from a list of general requirements, the first part of this chapter gives an overview of the dimensions of such a design. In addition, the various, often contradicting, architectural views that are relevant for the various stakeholders are discussed. Spec...

How to achieve health equity.

n engl j med 371;24 nejm.org december 11, 2014 2331 5. Pfeffer MA, Brenner BM, McMurray JJ. Aliskiren in type 2 diabetes and cardiorenal end points. N Engl J Med 2013;368:1065-6. 6. Luciano RL, Dahl NK. Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD): considerations for routine screening and management. Nephrol Dial Transplant 2014;29:247-54. 7. Chapman AB, To...

How Practice Makes Perfect