Houston, we have a problem…or do we? The trajectory of astrobioethics and Indigenous thought

Do We Know What We Do not Know? A Response to Celine Bonnet

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

admission and discharge from icu: do we have any protocol?

number of icu beds is one in the important indexes of providing health care for the critically ill patients around the world. lack of icu beds may delay admission to icu and causes patients’ poorer prognosis [1]. there are 20 and 15 icu beds/100,000 inhabitants in the usa and canada respectively. in european countries including germany, france and uk the number of icu beds per 100,000 persons i...

Aromatase Inhibitors for Endometriosis-Associated Infertility; Do We Have Sufficient Evidence?

Orally active aromatase inhibitors (AIs) have gained attention for treatment of infertile women with endometriosis in whom aromatase p450 is aberrantly expressed. This review aimed to critically appraise and summarize the available evidence concerning the use of AIs for management of endometriosis-associated infertility. PubMed was searched to May 2015 with the following key words: endometriosi...

How do we change practice when we have the evidence?

Translating research findings into practice includes myriad pragmatic realities, including understanding the suitability of the data to a particular patient group, writing new guidelines for occupational therapy practitioners, facilitating adoption of the guidelines, and instituting new patterns of care for patients. The process is more than a matter of disseminating the information to practiti...