Host associations and genomic diversity of Borrelia hermsii in an endemic focus of tick-borne relapsing fever in western North America
نویسندگان
چکیده
منابع مشابه
Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North America.
Borrelia hermsii is the primary cause of tick-borne relapsing fever in North America. When its tick vector, Ornithodoros hermsi, acquires these spirochetes from the blood of an infected mammal, the bacteria switch their outer surface from one of many bloodstream variable major proteins (Vmps) to a unique protein, Vtp (Vsp33). Vtp may be critical for successful tick transmission of B. hermsii; h...
متن کاملTick-borne Relapsing Fever Caused by Borrelia hermsii, Montana
Five persons contracted tick-borne relapsing fever after staying in a cabin in western Montana. Borrelia hermsii was isolated from the blood of two patients, and Ornithodoros hermsi ticks were collected from the cabin, the first demonstration of this bacterium and tick in Montana. Relapsing fever should be considered when patients who reside or have vacationed in western Montana exhibit a recur...
متن کاملBorrelia hermsii relapsing fever.
A 49-year-old healthy female presented to the emergency department with a headache, fever to 103°F, mild myalgia, heart rate of 119 bpm, and blood pressure of 80/40 mm Hg. Past medical history was unremarkable, no drug allergies or current medications, except for a recent vacation in eastern Washington state. The complete blood count showed a white blood cell count of 12.5 3 10E9/L (mild leukoc...
متن کاملChromosome and Plasmids of the Tick-Borne Relapsing Fever Agent Borrelia hermsii
The zoonotic pathogen Borrelia hermsii bears its multiple paralogous genes for variable antigens on several linear plasmids. Application of combined long-read and short-read next-generation sequencing provided complete sequences for antigen-encoding plasmids as well as other linear and circular plasmids and the linear chromosome of the genome.
متن کاملTick-borne Relapsing Fever and Borrelia hermsii, Los Angeles County, California, USA
The primary cause of tick-borne relapsing fever in western North America is Borrelia hermsii, a rodent-associated spirochete transmitted by the fast-feeding soft tick Ornithodoros hermsi. We describe a patient who had an illness consistent with relapsing fever after exposure in the mountains near Los Angeles, California, USA. The patient's convalescent-phase serum was seropositive for B. hermsi...
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ژورنال
عنوان ژورنال: Parasites & Vectors
سال: 2016
ISSN: 1756-3305
DOI: 10.1186/s13071-016-1863-0