Horse-Chestnut Seed Extract for Chronic Venous Insufficiency

Cochrane Summary of Findings: Horse Chestnut Seed Extract for Chronic Venous Insufficiency

As part of its efforts to disseminate the results of Cochrane reviews to a wider audience, the Cochrane Complementary and Alternative Medicine (CAM) Field develops Summary of Findings (SoF) tables and then uses these tables as a basis for its Plain Language Summaries. In each SoF table, the most important outcomes of the review, the effect of the intervention on each outcome, and the quality of...

Review: horse chestnut seed extract is effective for symptoms of chronic venous insufficiency.

Horse Chestnut (Aesculus Hippocastanum) for Venous Insufficiency

Submit Manuscript | http://medcraveonline.com glycosides and lactone glycosides, including protoaesigenin, barringeogenol-C, {reference 2) hippocaesculin, 6-E-glucoside7-hydroxy coumarin, and others, collectively called aescin (or occasionally escin). It also provides aesculic acid, aesculinic acid, an appreciable level of flavonoids (esculin, esculetin, rutin, kaempferol), tannins, starches, m...

Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies.

Extracts from the seed of the horse chestnut (Aesculus hippocastanum L.) have traditionally been used to treat patients with chronic venous insufficiency and to alleviate its associated symptoms, including lower leg swelling. The efficacy of preparations that contain horse chestnut seed extract (HCSE) is believed to be due largely to an inhibitory effect on the catalytic breakdown of capillary ...

Rational therapy of chronic venous insufficiency – chances and limits of the therapeutic use of horse-chestnut seeds extract

BACKGROUND AND METHODS We report two clinical studies, one already published, performed in patients with early and advanced chronic venous insufficiency (CVI). In both, compression therapy and oral therapy with horse-chestnut seeds extracts (HCSE) were compared to placebo. RESULTS The published study in early CVI (Grade I) showed HCSE and compression to be superior to placebo and to be equiva...