Hormones and Vasoprotection

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Hormones and Vasoprotection

There is a strong link between menopause and increased cardiovascular disease incidence in women, and observational studies suggest that postmenopausal hormone replacement therapy reduces cardiovascular disease risk by about half. Observational studies suffer from important limitations, however, and the only published prospective controlled trial of the effects of hormone replacement therapy on...

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Vasoprotection by Dietary Supplements and Exercise: Role of TNFα Signaling

Vascular dysfunction contributes to the pathogenesis of various cardiovascular diseases. Dietary supplements, including fish oil, dietary fibers, and various natural products, and exercise training exert vasoprotective effects. However, the mechanisms underlying the vasoprotective benefits of dietary supplements and physical activity demand extensive investigation. Accumulating evidence suggest...

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Striatin-dependent membrane estrogen receptor signaling and vasoprotection by estrogens.

It is well known that cardiovascular disease is less frequent in premenopausal women compared with men but rises rapidly in postmenopausal women. Such early observations led to the hypothesis that estrogen therapy will reduce the risk of postmenopausal women developing cardiovascular disease.1 However, observational studies have led to conflicting results, with some studies reporting reductions...

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Hormones and Sexual Disordors

The Paper is divided into two parts; at first: The role of endocrine system on anatomical development of internal and external sexual organs; Second part discusses the Endocrine View point of gender identity gender role, impotence, frigidity and other psychosexual disorders like homosexualism and transsexualism. 

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Vasoprotection by heme oxygenase-1: interactions with soluble guanylate cyclase

Background Heme oxygenase-1 (HO-1) is a highly inducible enzyme that metabolizes heme to generate equimolar amounts of carbon monoxide (CO), biliverdin, and ferrous iron. Subsequently, biliverdin is metabolized to the potent antioxidant bilirubin by biliverdin reductase. Compelling experimental evidence indicates that HO-1 and its end products protect against the development of vascular dysfunc...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1999

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.33.1.170