Homocystinuria: Amino Acid Pattern of the Liver

Free amino acid pattern in the liver from the patients with amino acid disorders: postmortem diagnosis of inborn errors of amino acid metabolism.

TADA, K., Y OSHIDA, T. and ARAAAWA, Ts. Free Amino Acid Pattern in the Liver from the Patients with Amino Acid Disorders: Postmortem Diagnosis of Inborn Errors of Amino Acid Metabolism. Tohoku J. exp. Med., 1970, 101 (3), 223-226 Free amino acid concentrations were determined in the liver biopsied or autopsied from the patients with amino acid disorder and from several controls. The results sho...

Correction of altered plasma amino acid pattern in cirrhosis of the liver by somatostatin.

The purpose of our study was to evaluate the effect of somatostatin (500 microgram/h intravenously) upon insulin, c-peptide, glucagon and plasma amino acids concentrations in patients with and without cirrhosis of the liver. The typical plasma amino acid pattern in cirrhosis is characterised by increased concentrations of the aromatic amino acids and decreased concentrations of the branched cha...

Inadequate laboratory technique for amino acid analysis resulting in missed diagnoses of homocystinuria.

The optimum dietary amino acid pattern for growing pigs. 1. Experiments by amino acid deletion.

A series of four nitrogen-balance experiments was carried out with growing pigs to determine the optimum balance amongst the amino acids in the diet. The reduction in N retention when 20% of a single amino acid was removed from the diet was used to calculate a dietary amino acid pattern in which each amino acid would be equally limiting. A mixture of amino acids simulating the amino acid patter...

The effect of chick-liver ribonucleic acid on amino acid-incorporation systems from rat liver.

1. Rat-liver microsomes, ribonucleoprotein particles and a fraction mainly consisting of microsomal membranes were tested for their ability to incorporate amino acids into protein in the presence of ATP, GTP, phosphoenolpyruvate and pyruvate kinase. Addition of polyuridylic acid or of ribonucleic acid from rat-liver nuclei stimulated the incorporating activities. 2. These protein-synthesizing s...