Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation
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چکیده
منابع مشابه
Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation
Myrf is a key transcription factor for oligodendrocyte differentiation and central nervous system myelination. We and others have previously shown that Myrf is generated as a membrane protein in the endoplasmic reticulum (ER), and that it undergoes auto-processing to release its N-terminal fragment from the ER, which enters the nucleus to work as a transcription factor. These previous studies a...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2017
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkx080