Homer W. Smith (1895-1962)

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چکیده

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Homer William Smith

This anthology commemorates a most unusual and complex person. Homer William Smith was best known as a renal physiologist whose work ranged from the evolution of the kidney to clinical studies on renal function and disease in man. He also studied and wrote about religion and philosophy, and published two novels, one of which, Kamongo, had rather a surprising success considering that its "plot" ...

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2008 Homer W. Smith Award: insights into the pathogenesis of polycystic kidney disease from gene discovery.

Polycystic kidney diseases (PKD) are a group of inherited disorders characterized by morbidity-associated development of renal cysts. Three forms of PKD are described here: The common, late onset, autosomal dominant PKD (ADPKD); the mainly infantile, autosomal recessive PKD (ARPKD); and the lethal, syndromic, Meckel syndrome that also includes central nervous system and digital defects. Positio...

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The legacy of Homer W. Smith: mechanistic insights into renal physiology.

In 1945, Homer W. Smith published an article in the JCI that clearly demonstrated that para-aminohippuric acid is the most suitable agent for the evaluation of renal plasma flow in both humans and dogs; in addition, the paper provided detailed methodology that is still in use today. This paper is but one of many outstanding works performed by Smith and his colleagues that clearly established th...

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2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage.

This overview summarizes selected major developments over the last 40 years in understanding podocyte biology and its involvement in glomerular disease subjectively from my perspective. Serendipity has played a major role in my contributions to investigative nephrology that range from basic mechanisms of immune deposit formation in experimental membranous nephropathy to the role of a microRNA i...

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Homer Smith: his contribution to physiology.

F or three decades, from the mid1930s until his death in 1962, Homer Smith was the preeminent figure among those interested in the physiology of the kidney. His leadership reflected not only the seminal research contributions of Smith and his colleagues and the conceptual framework that he developed, but also the extraordinary lucidity that he brought to the exposition of work in renal physiolo...

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ژورنال

عنوان ژورنال: Circulation

سال: 1962

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.26.5.984