Home recording of PEF in young asthmatics: does it contribute to management?

Home recording of PEF in young asthmatics: does it contribute to management?

The value of home monitoring of peak expiratory flow (PEF) as part of an action plan for asthma management in children and young adults is uncertain. We sought to determine whether home recording of PEF benefited asthma management and whether any contribution was affected by the severity of the asthma. Twenty-eight children and young adults with asthma of different severity (mean age 14 yrs; 95...

Endothelial Transcytosis of Insulin: Does It Contribute to Insulin Resistance?

Most research on insulin resistance has focused on impaired signaling at the level of target tissues like skeletal muscle. Insulin delivery is also important and includes recruitment and perfusion of capillaries bearing insulin, but also the transit of insulin across the capillary endothelium. The mechanisms of this second stage (insulin transcytosis) and whether it contributes to insulin resis...

KIR Gene Content Does Not Contribute to Susceptibility to Graves’ Disease

Background: Killer cell immunoglobulin-like receptors (KIR) are expressed on NK cells and a subset of T cells. The variable KIR receptors along with their ligands, HLA class I, influence risk for autoimmune and malignant diseases. Objective: To investigate the KIR gene profiles in relation to susceptibility to Graves’ disease in patients with ophthalmopathy. Methods: KIR genes profiles were ana...

Home recording of blood pressure in the management of hypertension.

The Physical Self-concept. What Does It Mean to Be Old: What Does It Mean to Be Young? the Physical Self-concept. What Does It Mean to Be Old: What Does It Mean to Be Young?

2 Does the concept of physical self remain stable across age? Or does the concept of physical self change as the body wearies and changes in shape? Do the components emphasised in our evaluation of our physical selves change with age or remain stable? Without evaluating such questions it is inappropriate to talk about Physical Self-Concept as though it is the same thing, with just different sco...