HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
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چکیده
منابع مشابه
IL-21 induces IL-22 production in CD4+ T-cells
Interleukin (IL)-22 produced by innate lymphoid cells (ILCs) and CD4+ T cells plays an important role in host defence and mucosal homeostasis, thus it is important to investigate the mechanisms that regulate IL-22 production. We investigated the regulation IL-22 production by CD4+ T cells. Here we show that IL-21 triggers IL-22, but not IL-17 production by CD4+ T cells. STAT3, activated by IL-2...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2010
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2010.36