HLA antigens and anti-sperm antibody

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HLA antigens and anti-sperm antibody production in Iranian vasectomized men

Dear Editor: Anti-sperm antibodies (ASAs) are composed of numerous antibodies interacting with multiple sperm antigens that play a role in fertility. In males, ASAs cause ‘immune infertility’ by decreasing sperm counts and normal forms, as well as reducing sperm motility and viability, markedly reducing the likelihood of natural conception [1] . The development of ASA in the male depends on the...

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Association of ABO Blood Group System and Anti-Sperm Antibody with Male Infertility

Background and Aims: The ABO blood group system is recognized as major and clinically significant blood group. This group is not only important in terms of blood transfusion and organ transplantation, but also has been utilized in genetic, fertility and infertility researches. The objective of the present study was to evaluate a possible relationship between ABO blood group system and ASA with ...

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Association between myasthenia gravis and HLA antigens in patients

Introduction: Myasthenia gravis is a disease of neuromuscular junction. Familial cases have been reported. Relation between myasthenia gravis and HLA antigens has been seen in many studies from different parts of the world. The aim of this study is determination of association between HLA class I haplotypes and myasthenia gravis in Kerman province. Methods: In this cross sectional study 44 my...

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HLA antigens and uveitis.

We have studied the antigen frequencies in a group of adult patients with acute and chronic iridocyclitis and chronic, cyclitis. In patients with iridocyclitis a statistically significant increased incidence of HLA-B27 was noted, even in those patients without joint or systemic disease. Patients with chronic iridocyclitis also were noted to have an increased incidence of B27; however, those pat...

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Background: Erythropoietin (EPO) was first known as a factor for red blood cell proliferation and differentiation. New studies show the effects of EPO on immune system. Objective: In this study, the effects of pretreatment with recombinant human erythropoietin (rHuEPO) on the anti-human leukocyte antibody (anti-HLA) titer were determined. Methods: Three groups of rats were sensitized with human...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2013

ISSN: 1664-3224

DOI: 10.3389/conf.fimmu.2013.02.00527