منابع مشابه
Quasars: What Turns Them Off?
While the high-redshift quasar luminosity function closely parallels the hierarchical growth of dark matter halos, at lower redshifts quasars exhibit an anti-hierarchical turn-off, which moves from the most luminous objects to the faintest. We explore the idea that this may arise from self-regulating feedback, caused by quasar outflows. Using a detailed hydrodynamic simulation we calculate the ...
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Background Adenosine as a stress agent is well tolerated and has a good safety profile but occasionally when administered at 140mg/kg/min it fails to produce a haemodynamic or symptomatic response. Studies have reported that between 4 18% patients do not respond to the standard dose . Splenic switch-off is a novel way of assessing adequacy of hyperaemic response, to adenosine. The aim of this s...
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The ATR-Claspin-Chk1 pathway is critical for turning on the cellular response to DNA damage and replication stress. Five recent reports uncover new mechanisms controlling the recovery phase of the checkpoint response, and introduce crucial roles for Claspin, Rad17 phosphorylation and the ubiquitin proteasome pathway in Chk1 signaling.
متن کاملBolA Is a Transcriptional Switch That Turns Off Motility and Turns On Biofilm Development
UNLABELLED Bacteria are extremely versatile organisms that rapidly adapt to changing environments. When bacterial cells switch from planktonic growth to biofilm, flagellum formation is turned off and the production of fimbriae and extracellular polysaccharides is switched on. BolA is present in most Gram-negative bacteria, and homologues can be found from proteobacteria to eukaryotes. Here, we ...
متن کاملOverweight and obese adolescents: what turns them off physical activity?
A systematic review of qualitative studies was undertaken to understand the barriers to physical activity experienced by adolescents who were overweight or obese. From a search of electronic databases and 'grey' literature, published between 1950 and 2009, 15 studies met the inclusion criteria. Bronfenbrenner's model of human development provided an ecological lens for identifying and synthesis...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2013
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.2597