HIV Receptors and Cellular Tropism
نویسندگان
چکیده
منابع مشابه
HIV-1 receptors and cell tropism.
HIV virus particles interact with several receptors on cell surfaces. Two receptors, CD4 and a co-receptor act sequentially to trigger fusion of viral and cellular membranes and confer virus entry into cells. For HIV-1, the chemokine receptor CCR5 is the predominant co-receptor exploited for transmission and replication in vivo. Variants that switch to use CXCR4 and perhaps other co-receptors e...
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ژورنال
عنوان ژورنال: IUBMB Life (International Union of Biochemistry and Molecular Biology: Life)
سال: 2002
ISSN: 1521-6543,1521-6551
DOI: 10.1080/15216540212652