HIV-1 detection in the olfactory mucosa of HIV-1-infected participants
نویسندگان
چکیده
منابع مشابه
A Simple and Rapid Method for the Detection of HIV-1/HCV in Co-Infected Patients
Background: Due to some limitations of serological methods in diagnosis of patients infected with HIV-1 (human immunodeficiency virus) and HCV (hepatitis C virus), it is profoundly important to use molecular methods for the detecting of these infectious agents. However, the most significant problems are the exorbitant cost of these methods and the need of a thermocycler which is an expensive...
متن کاملa simple and rapid method for the detection of hiv-1/hcv in co-infected patients
background: due to some limitations of serological methods in diagnosis of patients infected with hiv-1 (human immunodeficiency virus) and hcv (hepatitis c virus), it is profoundly important to use molecular methods for the detecting of these infectious agents. however, the most significant problems are the exorbitant cost of these methods and the need of a thermocycler which is an expensive in...
متن کاملHIV-1-specific CTLs effectively suppress replication of HIV-1 in HIV-1-infected macrophages.
Both CD4+ T cells and macrophages are major reservoirs of HIV-1. Previous study showed that HIV-1-specific cytolytic T lymphocytes (CTLs) hardly recognize HIV-1-infected CD4+ T cells because of Nef-mediated HLA class I down-regulation, suggesting that HIV-1 escapes from HIV-1-specific CTLs and continues to replicate in HIV-1-infected donors. On the other hand, the CTL recognition of HIV-1-infec...
متن کاملSLCO2B1 gene polymorphism and anti-retroviral therapy side effects in HIV-1 infected patients
Abstract Background and Objectives HIV virus and its subsequent disease is one of the most important challenges of the world health system. Although antiretroviral therapy (ART) is a breakthrough in patients’ life quality, it has complications like side effects. The side effect causes are diverse. One of the factors considered about side effects is genes polymorphism. This study investigates th...
متن کاملDetection of HIV-1-specific CTLs in the semen of HIV-infected individuals.
CTLs play an important role in controlling cell-associated HIV. Since the majority of HIV infections are acquired through sexual transmission, we investigated whether antiviral CTLs were present in the male urogenital tract using semen as a source of T cells. We were able to establish anti-HIV cytolytic lines in five of five HIV-infected men with CD4 counts of >500/microl, although cloning effi...
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ژورنال
عنوان ژورنال: AIDS
سال: 2019
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000002102