Historical Plaques: Images from the Missing Plaques Project

Pleural plaques.

Bilateral indurated violaceous non-tender plaques on the nasal ala

A 77-year-old Iranian man was visited at the Dermatology Department of Loghman-e Hakim Hospital affiliated with Shahid Beheshti University of Medical Sciences on June 2012 with bilateral, symmetric, raised, violaceous and painless plaques on the nose (both ala nasi), from one year ago. The lesions were small at first and then grew gradually larger in size. Systemic symptoms such as fever, weigh...

18F-choline images murine atherosclerotic plaques ex vivo.

OBJECTIVE Current imaging modalities of atherosclerosis mainly visualize plaque morphology. Valuable insight into plaque biology was achieved by visualizing enhanced metabolism in plaque-derived macrophages using 18F-fluorodeoxyglucose (18F-FDG). Similarly, enhanced uptake of 18F-fluorocholine (18F-FCH) was associated with macrophages surrounding an abscess. As macrophages are important determi...

F-Choline Images Murine Atherosclerotic Plaques Ex Vivo

Objective—Current imaging modalities of atherosclerosis mainly visualize plaque morphology. Valuable insight into plaque biology was achieved by visualizing enhanced metabolism in plaque-derived macrophages using Ffluorodeoxyglucose (F-FDG). Similarly, enhanced uptake of F-fluorocholine (F-FCH) was associated with macrophages surrounding an abscess. As macrophages are important determinants of ...

Subependymal plaques in scrapie-affected hamster brains--why are they so different from compact kuru plaques?

We report here routine thin-section and immunogold electron microscopic studies on diffuse plaques in scrapie-affected hamster brains. These plaques were not discernible by routine HE staining. Ultrastructurally, plaques were recognized as areas of low electron density containing haphazardly-oriented fibrils, but not as stellate compact structures typical of mouse scrapie models; hence we label...