Histone H3 lysine 27 trimethylation acts as an epigenetic barrier in porcine nuclear reprogramming
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منابع مشابه
Histone H3 lysine 27 trimethylation acts as an epigenetic barrier in porcine nuclear reprogramming.
Aberrant epigenetic reprogramming is the main obstacle to the development of somatic cell nuclear transfer (SCNT) embryos and the generation of induced pluripotent stem (iPS) cells, which results in the low reprogramming efficiencies of SCNT and iPS. Histone H3 lysine 27 trimethylation (H3K27me3), as a repressive epigenetic mark, plays important roles in mammalian development and iPS induction....
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2016
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-15-0338