HISTOLOGICAL OBSERVATIONS ON SLEEPING SICKNESS AND OTHER TRYPANOSOME INFECTIONS
نویسندگان
چکیده
منابع مشابه
The trypanosome lytic factor of human serum and the molecular basis of sleeping sickness.
Trypanosoma brucei brucei infects a wide range of mammals but is unable to infect humans because this subspecies is lysed by normal human serum (NHS). The trypanosome lytic factor is associated with High Density Lipoproteins (HDLs). Several HDL-associated components have been proposed as candidate lytic factors, and contradictory hypotheses concerning the mechanism of lysis have been suggested....
متن کاملCryptic stage of sleeping sickness trypanosome developing in choroid plexus epithelial cells.
Electronmicrographs of the choroid plexus from rats infected with Trypanosoma brucei rhodesiense showed that trypomastigotes from the perivascular spaces may penetrate and undergo multiple division in the ependymal cells which locally constitute the blood-brain barrier. Progressive degeneration of the ependymal cell liberates trypomastigotes back into the perivascular space, from which re-entry...
متن کاملIdentification of Trypanosome Proteins in Plasma from African Sleeping Sickness Patients Infected with T. b. rhodesiense
Control of human African sleeping sickness, caused by subspecies of the protozoan parasite Trypanosoma brucei, is based on preventing transmission by elimination of the tsetse vector and by active diagnostic screening and treatment of infected patients. To identify trypanosome proteins that have potential as biomarkers for detection and monitoring of African sleeping sickness, we have used a 'd...
متن کاملSleeping Sickness Wakes Again
Sleeping sickness of horses was, as reeentiy as the IQSO's, the most devastating livestock disease in the United States. Horses died by the hundreds of thousands in the Midwestern United States, in California, and along the Atlantic seaboard at a period which coincided with the beginning of the sharp decline in the use of horses on the farm. Losses were so severe in some areas that the inevitab...
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ژورنال
عنوان ژورنال: The Journal of Nervous and Mental Disease
سال: 1908
ISSN: 0022-3018
DOI: 10.1097/00005053-190802000-00011