Hippocampal volume in early onset depression
نویسندگان
چکیده
منابع مشابه
Hippocampal volume in early onset depression
BACKGROUND Abnormalities in limbic structures have been implicated in major depressive disorder (MDD). Although MDD is as common in adolescence as in adulthood, few studies have examined youth near illness onset in order to determine the possible influence of atypical development on the pathophysiology of this disorder. METHODS Hippocampal volumes were measured in 17 MDD subjects (age = 16.67...
متن کاملHippocampal volume change in depression: late- and early-onset illness compared.
BACKGROUND Evidence for structural hippocampal change in depression is limited despite reports of neuronal damage due to hypercortisolaemia and vascular pathology. AIMS To compare hippocampal and white matter structural change in demographically matched controls and participants with early-onset and late-onset depression. METHOD High-resolution volumetric magnetic resonance imaging (MRI) an...
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BACKGROUND There is a growing literature on the importance of hippocampal volume in geriatric depression. METHODS We examined hippocampal volume in a group of elderly depressed patients and a group of elderly control subjects (N = 66 geriatric depressed patients and 18 elderly nondepressed control subjects) recruited through Duke's Mental Health Clinical Research Center for the Study of Depre...
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OBJECTIVE Elevated levels of glucocorticoids in depression have been hypothesized to be associated with damage to the hippocampus, a brain area involved in learning and memory. The purpose of this study was to measure hippocampal volume in patients with depression. METHOD Magnetic resonance imaging was used to measure the volume of the hippocampus in 16 patients with major depression in remis...
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OBJECTIVE The purpose of this study was to investigate the effect of antidepressant treatment on hippocampal volumes in patients with major depression. METHOD For 38 female outpatients, the total time each had been in a depressive episode was divided into days during which the patient was receiving antidepressant medication and days during which no antidepressant treatment was received. Hippo...
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ژورنال
عنوان ژورنال: BMC Medicine
سال: 2004
ISSN: 1741-7015
DOI: 10.1186/1741-7015-2-2