Hindered Convection of Macromolecules in Hydrogels
نویسندگان
چکیده
منابع مشابه
Hindered convection of macromolecules in hydrogels.
Hindered convection of macromolecules in gels was studied by measuring the sieving coefficient (theta) of narrow fractions of Ficoll (Stokes-Einstein radius, r(s) = 2.7-5.9 nm) in agarose and agarose-dextran membranes, along with the Darcy permeability (kappa). To provide a wide range of kappa, varying amounts of dextran (volume fractions < or = 0.011) were covalently attached to agarose gels w...
متن کاملBiophysical Journal #2004/050302 (revised) Hindered Convection of Macromolecules in Hydrogels
Hindered convection of macromolecules in gels was studied by measuring the sieving coefficient (Q) of narrow fractions of Ficoll (Stokes-Einstein radius, r s = 2.7-5.9 nm) in agarose and agarose-dextran membranes, along with the Darcy permeability (k). To provide a wide range of k, varying amounts of dextran (volume fractions £ 0.011) were covalently attached to agarose gels with volume fractio...
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The ultimate goal of this research was to develop a greater understanding of the structural components needed to describe transport within the glomerular basement membrane (GBM). Specifically, dimensionless diffusive and convective hindrance factors were investigated by measuring macromolecular permeability through synthetic, two-fiber, agarose-dextran hydrogels at very small or very high Pe, r...
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A hindered urea bond (HUB), recently reported as a new type of dynamic chemical bond, can be facilely constructed by mixing an isocyanate and a hindered amine. Here, we report the use of the HUB in the design of degradable hydrogel materials for applications of stem cell encapsulation and delivery. Polyethyleneglycol (PEG) diamine was end-capped with a HUB and an allyl group in a one-pot synthe...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2005
ISSN: 0006-3495
DOI: 10.1529/biophysj.104.050302