Highly Efficient and Chemoselective Peptide Ubiquitylation
نویسندگان
چکیده
منابع مشابه
Highly efficient and chemoselective peptide ubiquitylation.
Post-translational modifications play an important role in regulating protein structure and function in health and disease. Ubiquitylation is one example for such a modification wherein both the extent (polyversus mono-ubiquitylation) and the sequence position of this modification dictates the function and fate of the ubiquitylated protein. In the ubiquitylation process, three distinct enzymes,...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2009
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.200902936