Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance

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Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance

Betatrophin/ANGPTL8 is a newly identified hormone produced in liver and adipose tissue that has been shown to be induced as a result of insulin resistance and regulates lipid metabolism. Little is known about betatrophin level in humans and its association with T2D and metabolic risk factors. Plasma level of betatrophin was measured by ELISA in 1603 subjects: 1047 non-diabetic and 556 T2D subje...

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Ceylon cinnamon does not affect postprandial plasma glucose or insulin in subjects with impaired glucose tolerance.

Previous studies on healthy subjects have shown that the intake of 6 g Cinnamomum cassia reduces postprandial glucose and that the intake of 3 g C. cassia reduces insulin response, without affecting postprandial glucose concentrations. Coumarin, which may damage the liver, is present in C. cassia, but not in Cinnamomum zeylanicum. The aim of the present study was to study the effect of C. zeyla...

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acute aerobic exercise and plasma levels of orexin a, insulin, glucose, and insulin resistance in males with type 2 diabetes

conclusions it seems that in people with type 2 diabetes, acute aerobic exercise can decrease the plasma levels of glucose, possibly through increasing orexin a. in addition, negative energy balance is necessary to decrease the levels of insulin and insulin resistance during acute aerobic exercise. results the analysis of findings in p ≤ 0.05 indicated that acute aerobic exercise caused a signi...

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Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

OBJECTIVE To quantitate plasma ceramide subspecies concentrations in obese subjects with type 2 diabetes and relate these plasma levels to the severity of insulin resistance. Ceramides are a putative mediator of insulin resistance and lipotoxicity, and accumulation of ceramides within tissues in obese and diabetic subjects has been well described. RESEARCH DESIGN AND METHODS We analyzed fasti...

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Effects of Eight Weeks Aerobic Exercise on Plasma Levels of Orexin A, Leptin, Glucose, Insulin, and Insulin Resistance in Males with Type 2 Diabetes

Objective: The recent study aimed to investigate the effects of chronic aerobic activity on the plasma levels of orexin A, leptin, glucose, insulin, and insulin resistance in males with type 2 diabetes. Materials and Methods: Twenty subjects randomly assigned into control and experimental groups, involving 10 people in each group. Exercise protocol consisted of eight session aerobic exercise...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2015

ISSN: 2045-2322

DOI: 10.1038/srep10949