Higher miR‐543 levels correlate with lower STK31 expression and longer pancreatic cancer survival
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چکیده
منابع مشابه
Lower Bmi-1 Expression May Predict Longer Survival of Colon Cancer Patients.
BACKGROUND This study aimed to investigate the Bmi-1 expression and the clinical significance in colon cancer (CC). PATIENTS AND METHODS Bmi-1 expression in tumor tissue and the corresponding normal tissue was detected using immunohistological staining. The correlations between Bmi-1 expression and clinicopathological characteristics and the overall survival (OS) time were analyzed. RESULTS...
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Differences in individual quality and survival within species are a major focus in evolutionary ecology, but we know very little about the underlying physiological mechanisms that determine these differences. Telomere shortening associated with cellular senescence and ageing may be one such mechanism. To date, however, there is little evidence linking telomere length and survival. Here, we show...
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PURPOSE The effect of cyclin D1 overexpression on breast cancer outcomes and prognosis is controversial, even though amplification of the cyclin D1 gene, CCND1, has been shown to be associated with early relapse and poor prognosis. In this study, we examined the relationship between cyclin D1 overexpression and disease-specific survival (DSS). We also analyzed survival in patients who experienc...
متن کاملLevels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase.
We recently reported that forced overexpression of the transcription factor E2F-1 in human HT-1080 fibrosarcoma cells resulted in corresponding high levels of thymidylate synthase (TS) and resistance to 5-fluoropyrimidines (D. Banerjee et al., Cancer Res., 58: 4292-4296, 1998). Because colorectal metastasis to the lung has higher TS levels than liver metastasis and is less responsive to treatme...
متن کاملCorrelate with Levels of Thymidylate Synthase Colon Cancer As Compared with Hepatic Metastasis and Levels of E2F-1 Expression Are Higher in Lung Metastasis of Updated Version
We recently reported that forced overexpression of the transcription factor E2F-1 in human HT-1080 fibrosarcoma cells resulted in corresponding high levels of thymidylate synthase (TS) and resistance to 5-fluoropyrimidines (D. Banerjee et al., Cancer Res., 58: 4292–4296, 1998). Because colorectal metastasis to the lung has higher TS levels than liver metastasis and is less responsive to treatme...
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ژورنال
عنوان ژورنال: Cancer Medicine
سال: 2020
ISSN: 2045-7634,2045-7634
DOI: 10.1002/cam4.3559