High SNAIL Expression Reflects Of Recurrence After Resection Colorectal Cancer Liver Metastasis
نویسندگان
چکیده
Introduction: Metastasectomy is one of the effective treatment methods for liver metastases developing from primary colorectal cancer (CRC). However, recurrence after metastasectomy biggest problem in these cancers. 
 The present study aimed to examine role Epithelial-Mesenchymal Transition (EMT) development CRCs.
 Materials and Methods: In study, 85 patients were evaluated. RNA was isolated archive tumors normal tissues patients. Expression profiles 7 different EMT markers examined using qRT-PCR.
 Results: Metastasis developed 24.7% (n=21) CRC. Recurrence observed 42.3% (n=9) metastasectomy. Statistically significant increases detected expression TWIST SNAIL mCC CRC (p
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ژورنال
عنوان ژورنال: Sakarya t?p dergisi
سال: 2022
ISSN: ['2146-409X']
DOI: https://doi.org/10.31832/smj.1128434