High-risk HPV16E6 stimulates hADA3 degradation by enhancing its SUMOylation
نویسندگان
چکیده
منابع مشابه
High-risk HPV16E6 stimulates hADA3 degradation by enhancing its SUMOylation.
Despite significant research, our understanding of the molecular mechanisms of Human Papilloma Virus (HPV) induced cancers remains incomplete. Majority of invasive cervical cancers are caused by high-risk HPV 16 and 18. Two potent HPV oncoproteins, E6 and E7, promote human malignancies by disrupting the activities of key regulators of cell proliferation and apoptosis. Recent investigations have...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2014
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/bgu104