High Resolution Micrograph of a Column

robust control of a high-purity disttilation column using synthesis

The Micrograph

A new instrument for observing and recording small changes of mechanical pressure by making use of the phenomena of the interference of light has recently been described. 1 Several important changes in the instrument have been made since the original communication, and the development of its applications has been in steady progress. In the present paper, an account is given of some results obta...

High-Resolution HLA-A Typing in Normal Iranian Population

Background: Human leukocyte antigen (HLA) gene is a highly polymorphic region. HLA typing is required to match patients and donors for transplantation; therefore, development of HLA registries is necessary for finding HLA match donors. HLA system is highly informative, and numerous studies have been conducted on HLA allele distribution in different populations. Methods: In this study,...

High-Resolution Separation of Oligonucleotides on a Pellicular Anion-Exchange Column

Multiple oligonucleotide (ON)-based therapeutic models have been developed to date including antisense oligonucleotides (ASOs), aptamer oligonucleotides (AOs) and short interfering RNA oligonucleotides (siRNA). In addition, modifications to oligonucleotide base-, backbone-, and ribosemoieties have all been introduced to limit nuclease-mediated degradation in therapeutic ONs. Mechanisms to resol...

Development of a High-Resolution Melting Method for Screening R188H Polymorphism in XRCC2 Gene

Background: The High Resolution Melting (HRM) method is a new scanning method for detecting unknown changes in DNA and its advantages have persuaded researchers to recruit it as a screening method. Objectives: Here, we developed a HRM method to screen R188H SNP (rs3218536) of XRCC2 and compared the results with a well known PCR-RFLP technique. Materials and Methods: Genomic ...