High-protein diet in diabetic nephropathy: what is really safe?

High-protein diet in diabetic nephropathy: what is really safe?

The well-trod controversy concerning the risks and benefits of limiting protein in the diet of patients with chronic kidney disease (CKD) has been raised again. In this issue of the Journal, Jesudason et al (1) have published their results from a comparison of 2 dietary prescriptions in subjects with suspected diabetic nephropathy, one prescription being higher in protein than the other. The co...

Is there really good news about pandemic diabetic nephropathy?

Defined in the dictionary as an adjective, the word pandemic, meaning: ‘occurring over a wide geographic area and affecting an exceptionally high proportion of the population,’ like epidemic, has evolved to its current usage as a noun [1]. In 2005, growth in number of individuals in the United States treated for end-stage renal disease (ESRD) was analysed using data generated by the United Stat...

Are we really in safe hands? How safe is safe?

The effect of a low-protein diet for diabetic nephropathy is underestimated.

We appreciate the opportunity to respond to the letter from Drs Bekaert and Rayman regarding our recently published article (1) on the association between plasma selenium concentrations and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Bekaert and Rayman point out that the mean plasma selenium concentration of EPIC participants is lower than th...

High fructose diet feeding accelerates diabetic nephropathy in Spontaneously Diabetic Torii (SDT) rats.

Diabetic nephropathy (DN) is one of the complications of diabetes and is now the most common cause of end-stage renal disease. Fructose is a simple carbohydrate that is present in fruits and honey and is used as a sweetener because of its sweet taste. Fructose has been reported to have the potential to progress diabetes and DN in humans even though fructose itself does not increase postprandial...