High-grade gliomas: a literature review. Part 2. Radiosurgical treatment

Malignant brain tumors remain one of the most complex problem in modern oncology, being among dangerous types cancer not only because their poor prognosis, but also due to immediate consequences for quality life and cognitive functions. It is expected that number such patients will increase as expectancy population increases.The mortality rate with malignant gliomas remains highest all patients. The median survival this does exceed 24.5 months. Despite serious progress study molecular biology type tumor, question effective application knowledge treatment process open.The review highlights advanced diagnostic methods analyzes effectiveness a multidisciplinary therapeutic strategy. Special attention given search new approaches radiosurgical high-grade order duration improve literature divided into 2 parts. Part 1 covers epidemiology, clinic, diagnosis gliomas, well combined approach disease. In 2nd part, issues stereotactic radiosurgery features practical “gamma knife” device pathology are highlighted; multimodal analyzed.