High-Gd-Payload P22 protein cage nanoparticles for imaging vascular inflammation
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چکیده
منابع مشابه
High-Gd-Payload P22 protein cage nanoparticles for imaging vascular inflammation
Methods 1) P22: The P22 protein cage (60 nm) is bioengineered with an internal polymer network with amine functional groups allowing incorporation of ~9100 Gd-DTPA molecules per cage via the amine groups (Figure 1: [1]). This provides a per cage relaxivity of 70000 mMs, superior to Gd-DTPA for the equivalent Gd concentration. 2) Atherosclerosis Models: Both ApoE-deficient (ApoE) and FVB mice we...
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ژورنال
عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance
سال: 2013
ISSN: 1532-429X
DOI: 10.1186/1532-429x-15-s1-o66