High flow nasal cannula (HFNC) with Heliox decreases diaphragmatic injury in a newborn porcine lung injury model

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In vitro comparison of heliox and oxygen in aerosol delivery using pediatric high flow nasal cannula.

Drug administration via high flow nasal cannula (HFNC) has been described in pediatrics but the amount of albuterol delivery with an HFNC is not known. The purpose of this study is to quantify aerosol delivery with heliox and oxygen (O(2)) in a model of pediatric ventilation. A vibrating mesh nebulizer (Aeroneb Solo, Aerogen) was placed on the inspiratory inlet of a heated humidifier and heated...

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High Flow Nasal Cannula Therapy in Neonatology

Introduction ........................................................ 1 List of Terms ....................................................... 2 High Flow Therapy (HFT) Defined .................... 2 Multiple Mechanisms of Action ........................ 3 HFT in the Context of Current Practices in Neonatal Respiratory Care ............................ 4 HFT: A Unique Noninvasive Respiratory Sup...

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Evaluation by various methods of the physiological mechanism of a high-flow nasal cannula (HFNC) in healthy volunteers

INTRODUCTION Several reports have described the usefulness of a high-flow nasal cannula (HFNC). However, the physiological mechanisms of this system are unclear. In the current study, various methods were used to investigate the physiological mechanisms of an HFNC in healthy volunteers. METHODS The physiological mechanisms of the constant-flow and constant-pressure models of HFNC were studied...

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Heliox delivered by high flow nasal cannula improves oxygenation in infants with respiratory syncytial virus acute bronchiolitis.

OBJECTIVE The objective of this study is to evaluate the hypothesis that use of heliox would result in improvement of gas exchange when used with high flow nasal cannula in infants with RSV acute bronchiolitis. METHODS All patients that met the inclusion criteria were randomized to either heliox (70:30) or air-oxygen mixture 30% via high flow nasal cannula at 8L/min for a continuous 24h. Meas...

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Effect of high-flow nasal cannula oxygen on diaphragmatic excursion and lung volumes determined by electrical impedance tomography

Results Twenty consecutive patients were included. The mean ARISCAT score was 41. The mean right diaphragmatic excursion was significantly increased with increasing inspiratory flow (baseline: 0.73 mm, 20l / min: 0.99 mm, 40l / min: 1.26 mm, 60l / min 1.51 mm, baseline. 0.66 mm, p < 0.0001). Linear regression analysis showed a dependent speed increase without ceiling effect. Lung volumes were a...

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ژورنال

عنوان ژورنال: Pediatric Pulmonology

سال: 2014

ISSN: 8755-6863

DOI: 10.1002/ppul.23000